Donor Health Updates

This web page is the place to find our public notice of any important updates to donor health history information that we obtain after the initial active listing for the donor is removed. We also attempt to individually notify clients that have reported success with the use of noted donors by mail or email if determined to be relevant.

099 - since his initial participation, this donor developed and was treated for testicular cancer, (the most common cancer in young men). posted 11/2006. There has been an offspring reported for this donor affected with Acute Lymphocytic Leukemia. It has been reported that the child is in remission at this time. Date of report was 7/2014. 

- We have a report of one child with very special needs that has growth and developmental problems diagnosed as SCS (Saethre-Chotzen's syndrome) and SCHAD (Short-chain-3-hydroxyacyl-CoA dehydrogenase deficiency).

All clients with children through the use of this donor are encouraged to become familiar with the syndromes possible traits and symptoms so that if they are found in a child, any possible treatments can be accessed as soon as possible. The donor does not display classical symptoms and knows of no biological family history in this regard. No mutation specific testing has been completed on the donor. To date, we have not had any other similar reports. posted 11/27/2006, updated 7/21/08.

086 - We have had a report of one child produced through the use of this donor with Medium Chain Acyl CoA Dehydrogenase Deficiency. This is an autosomal recessive disorder, that must be passed on by both parents for disease in the child, and has an incidence rate of between one in ten to twenty thousand births in one UK study. Anyone with children through the use of this donor are encouraged to become familiar with the problem, and should be aware that any children produced through the use of this donor may be a carrier for this genetic mutation. Current information is that this disease can be highly influenced by correct recognition and treatment.(rec 12/12/06) We have not yet received confirmation of this problem through a doctors report.

080F - We have a report of one child produced through the use of this donor diagnosed with SCN1A mutation causing refractory epilepsy. The donor has been tested and was found to be negative for this mutation. It was determined that this mutation in the child was spontaneous and not present in the donor.  10/2/15 We have a report of one child who was diagnosed with Type I diabetes.

297 - this donor listed 11/2006 was originally mistakenly listed at a higher weight and height than was correct, and was a simple transcription error only. We apologize! The information was corrected on 11/9/2006

4000- We have one report of a child experiencing epileptic type seizures at an age of a little over a year, with no cause yet diagnosed. The child was full term and has had normal growth and development since birth. We have no direct tie to the donor as explanation for this diagnosis. We do not have any other information at this time.

425 - One client experienced a miscarriage that was later determined to show a possible genetic cause for the loss which is not uncommon. This donor has shown other success without reported similar or dissimilar problems being reported. At this time the donor has sold out. We will post any further information as it is received. We understand that the client is proceeding with other genetic testing which may provide further information about the source of the problem. (received and posted 5/2/2007)

445 - We have one report, that if correct, would indicate that this donor is a carrier of congenital adrenal hyperplasia, CAH. We have had multiple reported uses with no complaint. To date, we have not had any other similar reports.

536 - By genetic relationship to donor 086, this donor is also assumed to be a carrier of the Medium Chain Acyl CoA Dehydrogenase Deficiency, MCADD. See number 086 above.(rec 12/12/06) We have had no reported problems with the use of this donor to date.

5302 -We have an (as of 5/31/07) unconfirmed report of a child with Celiac disease. The following information was obtained from a geneticist with a specialty in this disease. We do not promote the information as medical advice. Celiac disease is a disorder with a genetic link to two well known HLA molecules, DQ8 and DQ2 (with both Alpha and Beta subunits) coded for on chromosome 6. The presence of the genetic marker(s) is necessary but not sufficient for the development of the disease. In addition to the genetic predisposition, there are other factors (genetic and environmental) that contribute to the onset of Celiac disease. Having one or more of the markers is extremely common (30% of the population), but having one or more of the markers in your genetic makeup does not mean that you will have the disease. Under 5% of the people that have one or more of the genetic markers will develop the disease. This risk is elevated if there is a first degree family member with confirmed Celiac disease. Initial diagnosis is often made with antibody testing in symptomatic individuals and confirmatory testing is through biopsy of the intestinal tissue. The disease can be ruled out in individuals with a negative test result. Celiac disease is a chronic autoimmune disorder with multi-systemic manifestations. Ingestion of gluten-containing grains, especially wheat, can cause inflammation and damage of the small intestine. Infants with Celiac disease frequently present with failure to thrive. Diets avoiding gluten are followed by those that are diagnosed. As of 6/13/2007, this report of disease in the donor child is still unconfirmed.

As of 6/13/2007, we have now confirmed by DNA testing that the donor does carry the marker for the less common DQ8 molecule and half of the DQ2 molecule. This means that a child produced with this donor could be a carrier of the marker and if so would have a small chance of developing Celiac symptoms and disease, whether or not either marker is found in the mother. The donor does not have any evidence of developing the disease. Even though the donor is shown to be a carrier, it does not rule out the mother as carrier also, as one or more markers are found in 30% of the European and North American populations. Incidence for Celiac disease is only one in one hundred in the same population. This finding does not preclude the further use of this donor by clients with specimens in storage, but said clients will be notified of these findings as best we are able.

For more information, please contact your physician and read up through informative web resources such as

282G - There has been an offspring affected with Polydactyly reported for this donor. The child was born with an extra thumb on the right hand. Polydactyly is the most common of hand disabilities. It has been determined to occur as commonly as 1 in every 500 births. There are no instances of polydactyly in the donor's extended family which may imply the trait was inherited from the maternal side. Of the 12+ children conceived by this donor, this is the only report of this nature. If the trait came from the paternal donor we would expect to see 50% of the offspring affected.

280 - We received a report in June 2015 that this donor passed away due to Factor V Leiden. Upon notification of all recipients who reported a pregnancy with this donor, we received two reports of donor conceived children who are a carrier of the Factor V Leiden (R506Q) mutation

9169 - We received a medical report in July 2016 of an offspring from this donor born without a left kidney and with bilateral cognitive transient hearing loss.  The offspring presented with a 2-vessel cord and preterm labor at 24 weeks.  The mother experienced hypertension.