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Genetic carrier screening is performed on all donor applicants. The
specific tests performed on our donors has changed over time. Since
January 2011, we have been performing carrier screening for the
following disorders on all donor applicants:
Cystic fibrosis (CF) Spinal muscular atrophy (SMA) Tay Sachs/Hexosaminidase A deficiency Sickle cell anemia Beta-thalassemia Bloom syndrome Gauchers disease Canavan disease Fanconi anemia Type C Mucolipidosis Type IV Niemann Pick disease Type A
Donors who display the double helix icon on the donor catalog have been
screened for and tested negative as a carrier for these disorders.
Donors who entered the program prior to January 2011 do not have the
helix icon and have not had screening for all of these conditions.
with the double helix icon have also had carrier screening for an
expanded carrier screening panel and some donors have positive test
results for other disorders. These conditions are inherited in an
autosomal recessive manner which means that offspring of these donors
are not at risk to develop these conditions unless the other biological
parent also carries a mutation for the same condition. PRIOR to
selecting your donor, please contact us at email@example.com to obtain
specific information about the genetic screening performed on donors in
which you are interested.
We strongly recommend that you
review the full genetic test results for your donor with your healthcare
providers PRIOR TO insemination or embryo transfer so that you have the
opportunity to be informed about the risks associated with positive
test results as well as the options available for additional genetic
screening on yourself or your partner.
PLEASE NOTE: Genetic
screening can reduce the risk for specific conditions tested but does
not eliminate the risk for these conditions or for other untested
conditions. There is a 3 to 4% chance that any child could be born with
a birth defect, regardless of whether the child is conceived naturally
or through assisted reproductive technologies. It is not possible to
eliminate these risks or test for all of them before becoming pregnant.
counselors are healthcare professionals who can inform you about
genetic risks and genetic testing information. They can help you make
decisions about how much genetic testing, if any, is right for your
family. You can locate a genetic counselor in your area at www.nsgc.org .